The P2‐purinoceptor antagonist suramin is a competitive
Furthermore, NO synthase inhibitors greatly reduce VIP release in the canine ileum (Daniel et al., 1994), rabbit gastric fundus (Jin & Grider, 1993), rat colon (Grider, 1993), and guinea-pig gastric fundus (Grider et al., 1992) and small intestine (Grider & Jin, 1993). A NO-stimulated VIP release in the rat gastric fundus would explain the ...
Judge hears closing arguments in Christopher Grider Jan. 6 …
WASHINGTON (Gray DC) - Christopher Grider was at the scene of one of the most infamous January sixth moments, the shooting of Ashli Babbit outside the House of Representatives lobby. Grider says he was wrapped up in emotion, and never committed any violence. The prosecution and defense made their closing arguments beofre federal …
CHAPTER 1: Grinding of Waste Rubber
The word rubber originates from the South American Indian word, meaning 'weeping wood' and dictionary definition of rubber is, 'a material that when stretched returns quickly to its approximate original shape'. 1 A three dimensional insoluble and infusible chemical network is formed in the manufacturing of rubber products. This network is …
Epithelial 5-HT4 Receptors as a Target for Treating
This result was consistent with findings of Grider and colleagues [5, 6], ... Jin J-G, Foxx-Orenstein AE, Grider J (1999) Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors. J Pharmacol Exp Ther 288:93–97. CAS Google Scholar
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Epithelial 5-HT4 Receptors as a Target for Treating
This chapter focuses on our discovery of 5-HT4 receptors in the epithelial cells of the colon and our efforts to evaluate the effects of stimulating these receptors. 5-HT4 …
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11. The family of a man shot in August by his neighbor, an ex-cop, says the Sugar Land Police Department fumbled its investigation by favoring their former colleague's side of the story ...
The P2‐purinoceptor antagonist suramin is a …
Both suramin and α-chymotrypsin slightly inhibited relaxations to the NO-donor sodium nitroprusside, but not those to NO itself. It has previously been …
5-HT2B receptors play a key role in mediating the excitatory …
Introduction. Physiological and pharmacological studies have indicated that 5-HT may play a pivotal role in mediating sensory and reflex responses in the gastrointestinal tract of various species, including man (Read & Gwee, 1994).Whilst the receptors responsible for these effects in animals have been extensively investigated and subsequently identified, …
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For the series' main character, Geats, see Ace Ukiyo. Kamen Rider Geats (ライダーギーツ, Kamen Raidā Gītsu) is a Japanese Tokusatsu drama in Toei Company's Kamen Rider Series. It is the fourth series to debut in the Reiwa Era and the thirty-seventh overall. The series premiered on September 4, 2022, joining Avataro Sentai Donbrothers …
5-HT released by mucosal stimuli initiates peristalsis …
J R Grider 1, J F Kuemmerle, J G Jin. Affiliation. 1 Department of Physiology, Medical College of ia, Richmond 23298, USA. PMID: 8967488. DOI: …
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Jin (, Jin lit. "Quick") was a Humagear and founding member of MetsubouJinrai who transformed into Kamen Rider Jin (ライダー（ジン）, Kamen Raidā Jin). He was possessed by the Ark as Kamen Rider Ark-Zero (ライダーアークゼロ, Kamen Raidā Āku Zero) and later the Massbrain Systrem as Kamen Rider MetsubouJinrai (ライ …
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5-HT2B receptors play a key role in mediating the …
Introduction. Physiological and pharmacological studies have indicated that 5-HT may play a pivotal role in mediating sensory and reflex responses in the gastrointestinal tract of …
The P(2)-purinoceptor antagonist suramin is a competitive …
GRIDER J.R., JIN J.-G. Vasoactive intestinal peptide release and L-citrulline production from isolated ganglia of the myenteric plexus: evidence for regulation of vasocative intestinal peptide release by nitric oxide. Neuroscience. 1993; 54:521–526. [Google Scholar] GRIDER J.R., MURTHY K.S., JIN J.-G., MAKHLOUF G.M. Stimulation …
Tyrosine kinase involvement in apamin‐sensitive inhibitory …
Murthy, Murthy; Jin, Jin; Grider, Grider; Makhlouf, Makhlouf. Bookmark. Vasoactive intestinal peptide/pituitary adenylate cyclase‐activating peptide‐dependent activation of membrane‐bound NO synthase in smooth muscle mediated by pertussis toxin‐sensitive G i1–2.
Role of 5‐HT in the enteric nervous system and
The release of 5-HT from EC cells was thought to then activate intrinsic sensory nerve endings, which projected into the mucosa. Activation of the nerve endings of intrinsic sensory neurons was then believed to activate circuits in the myenteric plexus that caused peristalsis (Foxx-Orenstein et al., 1996; Grider et al., 1996; Jin et al., 1999).
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Glucocorticoids modulate brain function and behaviour through different mechanisms. Although classical effects are mediated through intracellular receptors that modulate gene transcription, recent evidence supports the existence of rapid, nongenomic steroid effects through the neuronal membrane. In this study, we explored possible rapid …
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(PDF) VIP/PACAP-dependent activation of membrane-bound …
The pathway involved in VIP/PACAP-stimulated NO formation in gastrointestinal smooth muscle is initiated by G protein-dependent stimulation of Ca 2ϩ influx and activation of eNOS bound to ...
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Distinct Populations of Sensory Neurons …
J. R. Grider and J-G. Jin Departments of Physiology and Medicine, Medical College of ia, Richmond, ia 23298 Recent studies suggest that muscle stretch and …
5-HT released by mucosal stimuli initiates peristalsis …
J. R. GRIDER, J. F. KUEMMERLE, AND J.-G. JIN Departments of Physiology and Medicine, Medical College of ia, Grider, J. R., J. F. Kuemmerle, and J.-G. Jin. …
5-Hydroxytryptamine4 receptor agonists initiate the …
Background & aims: The peristaltic reflex induced by mucosal stimuli is mediated by intrinsic sensory calcitonin gene-related peptide (CGRP) neurons activated by 5 …
Pituitary Adenylate Cyclase-Activating Polypeptide
Secretin is a gastrointestinal peptide and a member of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily Sherwood et al (2000). Secretin neutralizes acid in the intestine by effects on the pancreas Sherwood et al (2000), Banks et al (2002). In addition, secretin causes secretion of gastric pepsin, somatostatin ...
Interplay between Nitric Oxide and Vasoactive Intestinal
Nitric oxide (NO) and vasoactive intestinal polypeptide (VIP) interact in the regulation of neuromuscular function in the gut. They are also potent intestinal secretogogues that coexist in the enteric nervous system. The aims of this study were: (1) to investigate the interaction between NO and VIP in inducing fluid secretion in the rat …
Judge rules Central Texan guilty on all charges related to
A federal judge in Washington, D.C. found Central Texas vineyard owner Christopher Grider guilty Wednesday on all nine counts he was charged with in the Jan. 6, 2021, insurrection at the U.S. Capitol.
Tegaserod, Alimentary Pharmacology & Therapeutics | DeepDyve
Grider, Grider; Foxx‐Orenstein, Foxx‐Orenstein; Jin, Jin. Propulsion in guinea pig colon induced by 5‐hydroxytryptamine (HT) via 5‐HT4 and 5‐HT3 receptors. Jin, Jin; Foxx‐Orenstein, Foxx‐Orenstein; Grider, Grider. A selective 5‐HT 4 receptor agonist induces cAMP‐mediated Cl – efflux from rat colonocytes.